CJC1295 No DAC

Description

CJC-1295 No DAC is a synthetic growth hormone-releasing hormone (GHRH) analog based on the biologically active 1–29 region of GHRH. The 1–29 fragment has long been recognized as the shortest sequence that retains full biologic activity, which is why many later GHRH analogs were built from that core. CJC-1295 No DAC is a high-interest GHRH analog research peptide studied for its role in growth hormone-releasing hormone receptor signaling, pituitary GH release, and broader GH / IGF-1 axis investigation. Built on the active GHRH(1-29) framework, it is valued in laboratory settings for research involving endocrine signaling, pulsatile secretion models, and shorter-acting GHRH analog activity relative to DAC-linked long-acting forms.

In research settings, the no-DAC version is generally discussed for its relevance to:

• GHRH receptor signaling
• pituitary GH release
• GH / IGF-1 axis research
• pulsatile endocrine models
• shorter-acting secretagogue studies compared with DAC-linked forms